Contaminated open fracture and crush injury: a murine model
نویسندگان
چکیده
منابع مشابه
Open pelvic fracture due to crush injury.
© 2014 American Osteopathic Association A56-year-old man in hemorrhagic shock after being crushed at an industrial worksite had an open pelvic fracture involving the right sacrum and an unstable right hemipelvis (image A) as well as bilateral tibial fractures, a right femur fracture, and a nearly circumferential rectal laceration. The patient was placed in a pelvic binder and given cefazolin an...
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Patellar fracture is a relatively uncommon fracture especially the vertical sagittal type. In cases of high energy trauma injury, it is usually associated with fracture of ipsilateral distal femur or proximal tibia. However, the combination of vertical sagittal fracture patella and ipsilateral fracture lateral condyle is very rare. This necessitates judicious diagnosis and appropriate managemen...
متن کاملA new zebrafish bone crush injury model
While mammals have a limited capacity to repair bone fractures, zebrafish can completely regenerate amputated bony fin rays. Fin regeneration in teleosts has been studied after partial amputation of the caudal fin, which is not ideal to model human bone fractures because it involves substantial tissue removal, rather than local tissue injury. In this work, we have established a bone crush injur...
متن کاملComparison of the antimicrobial effect of chlorhexidine and saline for irrigating a contaminated open fracture model.
OBJECTIVES The objective of this study is to compare antimicrobial effect of irrigation with chlorhexidine gluconate (CHG) to saline in an animal model. METHODS This study used a segmental defect rat femur model contaminated with Staphylococcus aureus and treated 6 hours after injury with debridement and irrigation with 60 mL of fluid delivered at low pressure. In study groups of 10 animals e...
متن کاملA versatile model of open-fracture infection A CONTAMINATED SEGMENTAL RAT FEMUR DEFECT
Methods Defects were created in the stablised femurs of anaethetised rats, contaminated with Staphylococcus aureus and then debrided and irrigated six hours later. After 14 days, the bone and implants were harvested for separate microbiological analysis. This basic model was developed in several studies by varying the quantity of bacterial inoculation, introducing various doses of systemic anti...
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ژورنال
عنوان ژورنال: Bone Research
سال: 2015
ISSN: 2095-6231
DOI: 10.1038/boneres.2014.50